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Protein Domain : Voltage-gated hydrogen channel 1

Primary Identifier  IPR031846 Type  Family
Short Name  Hvcn1
description  Voltage-gated hydrogen channel 1 (Hvcn1, also known as Hv1 or VSOP) mediates the voltage-dependent proton permeability of excitable membranes. It forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient []. It is required for high-level superoxide production by phagocytes []. It has also been shown to regulate human sperm motility through activating alkalization-activated calcium channels []. The structure of Hvcn1 has been solved [].

0 Child Features

0 Parent Features

2 Protein Domain Regions