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Protein Domain : Herpesvirus UL16/UL94

Primary Identifier  IPR004286 Type  Family
Short Name  Herpes_UL16/UL94
description  UL16 protein (also known as cytoplasmic envelopment protein 2) plays a role in capsid maturation including DNA packaging/cleavage []. In immunofluorescence studies [], UL16 was localised to the nucleus of infected cells in areas containing high concentrations of Human herpesvirus 2 (Herpes simplex virus 2) capsid proteins. These nuclear compartments have been described previously as viral assemblons []and are distinct from compartments containing replicating DNA. Localization within assemblons argues for a role of UL16 encoded protein in capsid assembly or maturation [].UL94 is a human cytomegalovirus (HCMV) homologue that has been shown to be involved in facilitating secondary envelopment of virions [].

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