Primary Identifier | IPR041212 | Type | Domain |
Short Name | Vta1_C |
description | This is the C-terminal domain of the Vta1, which is a multivesicular body (MVB) protein. This domain promotes the ATP-dependent double ring assembly of Vps4. Furthermore, it has been shown that it is necessary and sufficient for protein dimerization. Mutations in Lys-299 and Lys-302 completely abolished the ability of Vta1 to stimulate the ATPase activity of Vps4 while mutation in Lys-322 had no effect []. |