Primary Identifier | IPR023762 | Type | Family |
Short Name | PGP_synthase_bac |
description | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (), also known as phosphatidylglycerophosphate synthase, glycerophosphate phosphatidyltransferase and PGP synthase, catalyses the conversion of CDP-diacylglycerol and glycerol-3-phosphate to CMP and 3-(3-phosphatidyl)-glycerol 1-phosphate in the committed step to the synthesis of acidic phospholipids. It is an integral membrane protein. A number of related enzymes are quite similar in both sequence and catalytic activity, including Saccharomyces cerevisiae (Baker's yeast) YDL142c, now known to be a cardiolipin synthase. There may be problems with incorrect transitive annotation of near homologues as authentic CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase.This entry represents a family of bacterial CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferases []. |