Primary Identifier | IPR016438 | Type | Family |
Short Name | Ski2-like |
description | This group represents a group of ATP-dependent RNA helicases and their homologues, including Ski complex protein Ski2 and RNA helicase Mtr4 (also known as Dob1). Ski2 is a putative RNA helicase that forms ski complex, which participates in many cytoplasmic pathways of the exosome in both yeast and metazoan cells, including 3'-to-5' mRNA turnover []. Mtr4 is a ATP-dependent 3'-5' RNA helicase involved in nuclear RNA processing and degradation [, ]. This entry also includes Arabidopsis AtMTR4 (AT1G59760) and HEN2 (AT2G06990), which target specific subsets of nuclear transcripts for degradation by the nuclear exosome []. |