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Protein Domain : Thrombospondin-5

Primary Identifier  IPR028492 Type  Family
Short Name  TSP-5
description  Cartilage oligomeric matrix protein (COMP), or thrombospondin-5 (TSP-5), is a member of the thrombospondin gene familyand is found mainly in the extracellular matrix often associated with cartilage tissue. It plays a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin [, , ]. COMP is involved in human limb development and in the pathogenesis of osteoarthritis [].

0 Child Features

0 Parent Features

6 Protein Domain Regions