| Primary Identifier | IPR028492 | Type | Family |
| Short Name | TSP-5 |
| description | Cartilage oligomeric matrix protein (COMP), or thrombospondin-5 (TSP-5), is a member of the thrombospondin gene familyand is found mainly in the extracellular matrix often associated with cartilage tissue. It plays a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin [, , ]. COMP is involved in human limb development and in the pathogenesis of osteoarthritis []. |