| Primary Identifier | IPR038066 | Type | Homologous_superfamily |
| Short Name | Spc24_Fungi_globular_sf |
| description | Spc24 is a component of the evolutionarily conserved kinetochore-associated Ndc80 complex, which is implicated in several essential outer kinetochore functions, including microtubule binding and control the spindle assembly checkpoint [, ].The Ndc80 complex appears to be a long rod with globular 'heads'. Ndc80 and Nuf2 contribute to one head and to the intervening shaft; Spc24 and Spc25 complete the shaft and contribute to the other head. Spc24 and Spc25 fold tightly together. TheC-terminal globular domains of Spc24 and Spc25 form the 'inner' head, which faces the centromere []. |
