| Primary Identifier | IPR005429 | Type | Family |
| Short Name | LimpII |
| description | Lysosome membrane protein II (LIMP II) is a 478-residue glycoproteinexpressed in the membrane of lysosomes and secretory granules with lysosomalproperties []. The N-terminal segment (residues ~4-26) constitutes an uncleavable signal peptide []. LIMP II possesses an additional C-terminalhydrophobic region that, together with the signal peptide, may anchor theprotein to the membrane []. The major portion of the protein resides ontheluminal side and contains 11 potential N-glycosylation sites and 5 cysteineresidues. The N- and C-terminal ends of the protein constitute short cytoplasmic tails. LIMP II is a subgroup of a larger family of the cell surface protein CD36 involved in cell adhesion. |
