| Primary Identifier | IPR016763 | Type | Family |
| Short Name | VAP |
| description | This entry represents a family of vesicle-associated membrane-protein-associated proteins (VAPs) and plant VAP homologs (PVAPs) []. VAPs (VAPA and VAPB in humans, VAPA, VAPB and VAPC in other mammals []) are endoplasmic reticulum (ER) proteins that play roles in vesicle trafficking, neurotransmitter release, microtubule organisation, lipid transport and unfolded protein response []. VAP proteins contain an MSP domain in their N-terminal half, which has been shown to interact with proteins containing a FFAT motif, such as members of the oxysterol-binding protein (OSBP) family or the phosphatidylinositol transfer proteins from the PITPNM family []. Yeast VAP homologues are known as Scs2 and Scs22 []. |
