| Primary Identifier | IPR026155 | Type | Family |
| Short Name | Apelin |
| description | Apelin is a bioactive peptide with a wide variety of physiological actions, which are mediated by its interaction with its specific G protein-coupled receptor, APJ []. The protein is cleaved into several different active forms, including apelin-36, apelin-17 and apelin-13. Apelin has been shown to be involved in the regulation of cardiovascular and fluid homeostasis, food intake, cell proliferation, and angiogenesis []. It has also been shown to inhibit human immunodeficiency virus type 1 entry into cells coexpressing CD4 and APJ []. |
