| Primary Identifier | IPR026128 | Type | Family |
| Short Name | VGF |
| description | VGF protein is a neurosecretory protein originallyidentified as a product of the nerve growth factor responsivegene Vgf in rat pheochromocytoma PC12 cells [, ]. VGF may be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the nervous system []. Neuroendocrine regulatory peptides (NERP)-1 and NERP-2 are bioactive peptides processed from VGF and involved in the control of body fluid homeostasis by regulating vasopressin release. Administration of NERPs suppresses hypertonic saline- or angiotensin II-induced vasopressin release from the hypothalamus and pituitary []. |
