Primary Identifier | IPR038172 | Type | Homologous_superfamily |
Short Name | Herpes_glycoH_C_sf |
description | Herpesvirus glycoprotein H (gH) is a virion associated envelope glycoprotein []. Complex formation between gH and gL has been demonstrated in both virions and infected cells []. This superfamily represents the C-terminal domain.Structurally, the C-terminal domain consists of 8 beta sheets and 1 small alpha helix. The beta sheets are arranged into a beta sandwich, made up of two apposed beta sheets, each made up of four strands. Within Herpesvirus glycoprotein H, the two sheets are termed the N sheet and C sheet, since they are sequential. The alpha helix sits in the loop between two of the beta strands, and packs against the C sheet. |