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Protein Domain : Herpesvirus glycoprotein H, C-terminal domain superfamily

Primary Identifier  IPR038172 Type  Homologous_superfamily
Short Name  Herpes_glycoH_C_sf
description  Herpesvirus glycoprotein H (gH) is a virion associated envelope glycoprotein []. Complex formation between gH and gL has been demonstrated in both virions and infected cells []. This superfamily represents the C-terminal domain.Structurally, the C-terminal domain consists of 8 beta sheets and 1 small alpha helix. The beta sheets are arranged into a beta sandwich, made up of two apposed beta sheets, each made up of four strands. Within Herpesvirus glycoprotein H, the two sheets are termed the N sheet and C sheet, since they are sequential. The alpha helix sits in the loop between two of the beta strands, and packs against the C sheet.

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