| Primary Identifier | IPR038157 | Type | Homologous_superfamily |
| Short Name | FeoA_core_dom |
| description | This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found in bacteria. This domain also occurs at the C terminus in the diphtheria toxin repressor (DtxR). DtxR is a iron-binding repressor that contains two domains separated by a short linker. The C-terminal domain adopts a fold similar to eukaryotic Src homology 3 domains, but its functional role is unknown [].The transporter Feo is composed of three proteins: FeoA a small, soluble SH3-domain protein probably located in the cytosol; FeoB, a large protein with a cytosolic N-terminal G-protein domain and a C-terminal integral inner-membrane domain containing two 'Gate' motifs which likely functions as the Fe2+ permease; and FeoC, a small protein apparently functioning as an [Fe-S]-dependent transcriptional repressor [, ]. Feo allows the bacterial cell to acquire iron from its environment. |
