| Primary Identifier | IPR003892 | Type | Domain |
| Short Name | CUE |
| description | This domain promotes intramolecular monoubiquitination and has a dual role in mono- and poly-ubiquitination recognition, being involved in binding ubiquitin-conjugating enzymes (UBCs) [, , ]. CUE domains also occur in two proteins of the IL-1 signal transduction pathway, tollip and TAB2. |