| Primary Identifier | IPR035618 | Type | Domain |
| Short Name | RBM10_OCRE |
| description | RBM10 contains two N-terminal RNA recognition motifs (RRMs) and an OCtamer REpeat (OCRE) domain, two C2H2-type zinc fingers, and a G-patch/D111 domain. This entry represents the OCRE domain.RBM10, also known as S1-1, is a nuclear RNA-binding protein with domains characteristic of RNA processing proteins.Similar to RBM5, it promotes exon skipping of Fas pre-mRNA as well as selection of an internal 5'-splice site in Bcl-x pre-mRNA []. It preferentially binds to G- and U-rich RNA sequences [].The OCRE (OCtamer REpeat) domain contains five repeats of an 8-residue motif, which were shown to form β-strands. Based on the architectures of proteins containing OCRE domains, a role in RNA metabolism and/or signalling has been proposed []. |
