| Primary Identifier | IPR028619 | Type | Family |
| Short Name | DEAD_helicase_DbpA |
| description | RNA helicases from the DEAD-box family are found in almost all organisms andhave important roles in RNA metabolism, such as splicing, RNA transport,ribosome biogenesis, translation and RNA decay. They are enzymes that unwinddouble-stranded RNA molecules in an energy dependent fashion through thehydrolysis of NTP. DEAD-box RNA helicases belong to superfamily 2 (SF2) ofhelicases. As other SF1 and SF2 members they contain seven conserved motifswhich are characteristic of these two superfamilies [].DEAD-box is named after the amino acids of motif II or Walker B (Mg2+-bindingaspartic acid). The RNA helicase DbpA has an RNA-dependent ATPase activity, which is specific for 23S rRNA [, ]. It is involved in assembly of the 50S ribosomal subunit []. |
