| Primary Identifier | IPR016608 | Type | Family |
| Short Name | PRDM1 |
| description | PR domain zinc finger protein 1 (PRDM1, also known as BLIMP-1) is a transcriptional repressor that is essential for cellular development. This entry includes BLIMP-1 from vertebrates and its homologues from invertebrates. In vertebrates, PRDM1 is also known as B lymphocyte-induced maturation protein 1 (BLIMP-1) or positive regulatory domain I-binding factor (PRDI-BF1). It is essential for the differentiation of B and T cells []. In Caenorhabditis elegans, it regulates the spatiotemporal cell migration pattern []. The degradation of PRDM1 by DRE-1/FBXO11-dependent mechanism regulates the C. elegans developmental timing and maturation []. |
