| Primary Identifier | IPR004621 | Type | Family |
| Short Name | Fadh2_euk |
| description | This entry represents a family that includes methylenetetrahydrofolate reductase.The enzyme activities methylenetetrahydrofolate reductase () and 5,10-methylenetetrahydrofolate reductase (FADH) () differ in that the former (assigned in many eukaryotes) is defined to use NADP+ as an acceptor, while the latter (assigned in many bacteria) is flexible with respect to the acceptor. Both convert 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolate. From a larger set of proteins assigned as one or the other, this family describes the subset of proteins found in eukaryotes, and currently designated methylenetetrahydrofolate reductase(). This protein is an FAD-containing flavoprotein. |
