| Primary Identifier | IPR004620 | Type | Family |
| Short Name | MTHF_reductase_bac |
| description | This entry represents a family that includes bacterial 5,10-methylenetetrahydrofolate reductase (FADH).The enzyme activities methylenetetrahydrofolate reductase () and 5,10-methylenetetrahydrofolate reductase (FADH) () differ in that the former (assigned in many eukaryotes) is defined to use NADP+ as an acceptor, while the latter (assigned in many bacteria) is flexible with respect to the acceptor. Both convert 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolate. From a larger set of proteins assigned as one or the other, this family describes the subset of proteins found in prokaryotes, and currently designated 5,10-methylenetetrahydrofolate reductase (FADH) (). This protein is an FAD-containing flavoprotein. |
