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Protein Domain : Synaptotagmin-5

Primary Identifier  IPR028689 Type  Family
Short Name  SYT5
description  Synaptotagmin-5 (SYT5) belongs to the synaptotagmin family, which is a group of membrane-trafficking proteins that contain two C-terminal C2 domains. Most of the synaptotagmins have a unique N-terminal domain that is involved in membrane anchoring or specific ligand binding. SYT5 is involved in the Ca2+-dependent stimulation of insulin exocytosis []. SYT5 is also known as synaptotagmin IX (SYT9) in rodents. In PC12 (phaeochromocytoma) cells, it regulates Ca2+-dependent secretion [].

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1 Protein Domain Regions