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Protein Domain : YY1-associated factor 2

Primary Identifier  IPR038039 Type  Family
Short Name  YAF2
description  YY1-associated factor 2 (YAF2) binds to MYC and MYCN, inhibiting MYC-mediated transactivation and enhances MYCN-dependent transcriptional activation [, ]. It interacts with YY1, which is down-regulated at the protein level during myogenic differentiation, enhancing its degradation by calpain 2 []. It is a component of the E2F6.com-1 complex in G0 phase of the cell cycle []. YAF2 contains a RanBP2-type zinc finger.
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Trail: ProteinDomain




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