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Protein Domain : PHF13, PHD finger

Primary Identifier  IPR041947 Type  Domain
Short Name  PHD_PHF13
description  PHF13, also termed survival time-associated PHD finger protein in ovarian cancer 1 (SPOC1), is a novel plant homeodomain (PHD) finger-containing protein that shows strong expression in spermatogonia and ovarian cancer cells, modulates chromatin structure and mitotic chromosome condensation, and is important for proper cell division. It is also required for spermatogonial stem cell differentiation and sustained spermatogenesis. The overexpression of PHF13 associates with unresectable carcinomas and shorter survival in ovarian cancer [, , , ].This entry represents the PHD finger found in PHF13.

0 Child Features

1 Parent Features

3 Protein Domain Regions