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Protein Domain : Gawky, UBA domain

Primary Identifier  IPR041971 Type  Domain
Short Name  Gawky_UBA
description  This entry represents the UBA domain of Gawky.Protein Gawky (also known as GW182) plays a role in RNA-mediated gene silencing by micro-RNAs (miRNAs) [, ]. It is a component of cytoplasmic mRNA processing bodies required for early Drosophila development []. GW182 interacts with AGO1, and this interaction is essential for silencing by miRNAs []. It recruits the CCR4-NOT deadenylase complex through the interaction with PABPC1 [].

0 Child Features

1 Parent Features

0 Protein Domain Regions