Primary Identifier | IPR038325 | Type | Homologous_superfamily |
Short Name | IL7_sf |
description | This entry represents interleukin-7 (IL7), it is a hematopoietic growth factor produced by bone marrow stromal cells. It promotes growth of B- and T-cell precursors and functions with IL2 in the activation of mature T-cells [, ]. IL-7 and IL-7Ralpha bind the gamma-c receptor forming a complex required for the development and homeostasis of T and B cells []. Interleukin-7 and Interleukin-9 belong to the same larger family. |