| Primary Identifier | IPR038184 | Type | Homologous_superfamily |
| Short Name | CSTF1_dimer_sf |
| description | This entry represents the dimerisation domain found at the N terminus of cleavage stimulation factor subunit 1 (CSTF1) from eukaryotes. This domain allows for homodimerisation such that the functional state of CSTF1 is a heterohexamer. The Cleavage stimulation Factor (CstF) complex is composed of three subunits and is essential for pre-mRNA 3'-end processing. CstF recognises U and G/U-rich cis-acting RNA sequence elements and helps to stabilise the Cleavage and Polyadenylation Specificity Factor (CPSF) at the polyadenylation site as required for productive RNA cleavage []. |
