Primary Identifier | IPR028818 | Type | Family |
Short Name | NCOA3 |
description | Nuclear receptor coactivator 3 (NCOA3, also known as AIB1) belongs to the SRC/p160 nuclear receptor coactivator family, which contains proteins that are ligand-dependent transcription factors []. These receptors can function as molecular switches [].NCOA3 is overexpressed in a fraction of breast cancers and has been linked to prognosis and tamoxifen resistance [, ]. |