| Primary Identifier | IPR028804 | Type | Family |
| Short Name | SSX |
| description | This entry represents the SSX family, including SSX1-9. They are identified as cancer testis antigens and can act as a transcription modulator. Some members of this family can become fused to the SS18 protein in synovial sarcoma (SS) through gene translocations []. In humans, SSX1-9 have a N-terminal KRAB (Krüppel-associated box) domain and a C-terminal RD (repression domain). The RD domain mediates repression of transcription and can be translocated to the C-terminal end of SYT in synovial sarcoma []. |
