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Protein Domain : Cytoplasmic tyrosine-protein kinase BMX

Primary Identifier  IPR028840 Type  Family
Short Name  BMX
description  Cytoplasmic tyrosine-protein kinase BMX (bone marrow tyrosine kinase gene on chromosome X, also known as ETK) is a non-receptor tyrosine kinase (). It plays central but diverse modulator roles in various signalling processes involved in the regulation of actin reorganisation, cell migration, cell proliferation and survival, cell adhesion, and apoptosis [, , ]. It has a role in inflammation, cardiovascular disease, and cancer []. It is activated downstream of phosphatidylinositol-3 kinase (PI3K) andthe kinase Src [].

0 Child Features

0 Parent Features

4 Protein Domain Regions