| Primary Identifier | IPR041804 | Type | Domain |
| Short Name | Vps9_CUE |
| description | Vps9 is a cytosolic yeast protein required for localization of vacuolar proteins, such as the soluble vacuolar hydrolases CPY and PrA []. It may bind and act as an effector of a Rab GTPase and plays a role in vacuolar protein sorting (VPS) pathway. Vps9 contains a region called GBH domain that is related to mammalian Ras-binding proteins, Rin1 and JC265, and may negatively regulate Ras-mediated signaling in yeast Saccharomyces cerevisiae. This entry represents the N-terminal CUE domain that interacts specifically with monoubiquitin and regulates intramolecular monoubiquitylation [, ]. |
