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Protein Domain : Transcription initiation factor Rrn11

Primary Identifier  IPR007224 Type  Family
Short Name  TIF_Rrn11
description  The RNA polymerase I specific transcription initiation factor Rrn11 is a member of a multiprotein complex essential for the initiation of transcription by RNA polymerase I, together with Rrn6 and Rrn7 subunits [, ]. Binding to the DNA template is dependent on the initial binding of other factors []. Rrn11 contains a tetratricopeptide repeats (TPRs) and interacts with Rrn6 and Rrn7 to form the core factor (CF), which resembles a right hand holding the DNA molecule between the fingers and the palm. The palm is composed of the N-terminal regions of both Rrn11 and Rrn6, the thumb is composed of the C-terminal of Rrn11, and the fingers and knuckles are composed of Rrn7 and the C-terminal half of Rrn6, respectively [].

1 Child Features

0 Parent Features

0 Protein Domain Regions