| Primary Identifier | IPR028880 | Type | Family |
| Short Name | Rrm3 |
| description | This entry represents ATP-dependent DNA helicase Rrm3 from buddingyeasts. It is a 5' to 3' DNA replicative helicase recruited to paused replisomes to promote fork progression throughout nonhistone protein-DNA complexes, naturally occurring impediments that are encountered in each S phase where replication forks pauses []. It shares protein sequence similarities with another DNA helicase, Pif1. However, their functions are different. Rrm3 promotes telomere replication, while Pif1 inhibits telomere replication []. They also have opposite effects on replication fork progression in ribosomal DNA []. |
