| Primary Identifier | IPR026266 | Type | Family |
| Short Name | AraF |
| description | Periplasmic L-arabinose-binding protein (ABP) is involved in the high-affinity L-arabinose membrane transport system. It binds with high affinity to arabinose, but can also bind D-galactose (at approximately 2-fold lower affinity) and D-fucose (at approximately 40-fold lower affinity) [, ].The periplasmic ABP consists of two alpha/beta globular domains connected by a three-stranded hinge, a Venus flytrap-like domain, which undergoes a transition from an open to a closed conformational state upon ligand binding. Moreover, ABP is homologous to the ligand-binding domain of eukaryotic receptors such as metabotropic glutamate receptor (mGluR) and DNA-binding transcriptional repressors such as LacI and GalR []. |
