| Primary Identifier | IPR038239 | Type | Homologous_superfamily |
| Short Name | Clp1_N_sf |
| description | Clp1 function involves some degree of adenine or guanine nucleotide binding and participates in the 3' end processing of mRNAs in eukaryotes []. Both human Clp1 (hsClp1) and Saccharomyces cerevisiae Clp1 (scClp1) were identified as components of the pre-mRNA 3end-processing machinery. Whereas hsClp1 was shown to also be part of the tRNA endonuclease complex, scClp1 exclusively contributes to mRNA maturation and appears to be enzymatically inactive.Clp1 contains three domains, a small N-terminal beta sandwich domain, a C-terminal domain containing a novel alpha/β-fold and a central domain that binds ATP [, ]. This entry represents the N-terminal domain involved in DNA binding []. |
