| Primary Identifier | IPR038564 | Type | Homologous_superfamily |
| Short Name | Maf1_sf |
| description | Maf1 is a negative regulator of RNA polymerase III [, ]. It inhibits the de novo assembly of TFIIIB onto DNA []. Maf1 represses Pol III in response to DNA damage, oxidative stress, growth to stationary phase, treatment with rapamycin or chlorpromazine, and blocking of the secretory pathway []. It targets the initiation factor TFIIIB []. Its structure is composed of a central five-stranded antiparallel β-sheet that is flanked by one helix on one side and three helices on the other []. |
