Primary Identifier | IPR038738 | Type | Domain |
Short Name | Nedd8-like |
description | Nedd8 (also known as Rub1) has a single conserved ubiquitin-like domain that is part of a protein modification pathway similar to that of ubiquitin []. Nedd8 modifies a family of molecular scaffold proteins called cullins that are responsible for assembling the ROC1/Rbx1 RING-based E3 ubiquitin ligases, of which several play a direct role in tumorigenesis []. This entry also includes Nedd8-like proteins from fungi and plants. |