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Protein Domain : Transcription factor DEAF-1

Primary Identifier  IPR024119 Type  Family
Short Name  TF_DEAF-1
description  Deformed epidermal autoregulatory factor-1 (DEAF-1) was first isolated in Drosophila melanogaster as a novel DNA-binding protein []. Since then, several orthologues in mammals have been identified. In Drosophila, DEAF-1 plays an important role in embryonic development, particularly in the segmentation stage following cuticle secretion. In mammals it regulates different processes, including epithelial cell proliferation and side-branching in the mammary gland []and it is required for neural tube closure and skeletal patterning [].

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0 Parent Features

8 Protein Domain Regions