| Primary Identifier | IPR045256 | Type | Domain |
| Short Name | RanBP1_RanBD |
| description | This entry represents the Ran-binding domain (RBD) found in RanBP1 from humans and Yrb1 from budding yeasts. RanBP1 and Yrb1 are involved in nuclear import and export. RanBP1 and Yrb1 have been shown to shuttle between the nucleus and cytoplasm and the conserved RBD is necessary and sufficient for the essential function and nucleocytoplasmic shuttling []. RanBP1/Yrb1 acts as a negative regulator of Regulator of chromosome condensation 1 (RCC1) by inhibiting RCC1-stimulated guanine nucleotide release from Ran []. |
