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Protein Domain : Alpha-tubulin N-acetyltransferase

Primary Identifier  IPR038746 Type  Family
Short Name  Atat
description  Alpha-tubulin N-acetyltransferase was originally known as mechanosensory abnormality protein 17 (Mec-17), as it is the protein product of one of the 18 genes required for the development and function of the touch receptor neuron for gentle touch []. Mec-17 specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules []. It is inefficient, and its activity is enhanced when tubulin is incorporated in microtubules []. It may affect microtubule stability and regulate microtubule dynamics. It can function as an enzymatic timer for microtubule lifetimes [].

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4 Protein Domain Regions