| Primary Identifier | IPR024031 | Type | Family |
| Short Name | MSMEG_5819/OxyR |
| description | F420 (or 8-hydroxy-5-deazaflavin) is a coenzyme involved in redox reactions in methanogens. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomycetales, make F420. This subfamily within the PPOX family occurs in at least 19 distinct species of F420 producers and is likely to bind F420 rather than FMN (flavin mononucleotide or riboflavin-5'-phosphate). The member OxyR was shown in Streptomyces rimosusto use F420 to catalyze a C5a-C11a reduction in tetracycline or oxytetracycline biosynthesis [, ], and OxyR is also known as 5a,11a-dehydrotetracycline/5a,11a-dehydrooxytetracycline reductase. |
