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Protein Domain : WASP homologue-associated protein with actin, membranes and microtubules

Primary Identifier  IPR026688 Type  Family
Short Name  WHAMM
description  WASP homologue-associated protein with actin, membranes and microtubules (WHAMM) contains three domains, an N-terminal domain that mediates Golgi membrane association, a coiled-coil region that binds microtubules, and one or two WH2 domains that stimulate Arp2/3-mediated actin polymerisation. It acts as a nucleation-promoting factor (NPF) that stimulates Arp2/3-mediated actin polymerisation both at the Golgi apparatus and along tubular membranes. It is involved as a regulator of Golgi positioning and morphology. It also participates in vesicle transport between the reticulum endoplasmic and the Golgi complex [].

0 Child Features

0 Parent Features

2 Protein Domain Regions