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Protein Domain : MTMR10, PH-GRAM domain

Primary Identifier  IPR036004 Type  Domain
Short Name  MTMR10_PH-GRAM
description  The family of myotubularin (MTM) phosphoinositide phosphatases includes catalytically inactive members, or pseudophosphatases, which contain inactivating substitutions in the phosphatase domain []. Myotubularin-related protein 10 (MTMR10) is a probable pseudophosphatase.MTMR10 contains an N-terminal PH-GRAM domain, a Rac-induced recruitment domain (RID) domain, an inactive PTP domain, and a SET interaction domain. It contains a Glu residue instead of a conserved Cys residue in the dsPTPase catalytic loop which renders it catalytically inactive as a phosphatase. This entry represents the PH-GRAM domain of MTMR10.

0 Child Features

0 Parent Features

1 Protein Domain Regions