| Primary Identifier | IPR036081 | Type | Homologous_superfamily |
| Short Name | Translin_sf |
| description | Translins are DNA-binding proteins that specifically recognise consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. They seem to recognise single-stranded DNA ends generated by staggered breaks occuring at recombination hot spots []. Translin folds into an α-α superhelix, consisting of two curved layers of alpha/alpha topology [, ].This entry also includes translin-associated protein X (TRAX), which was found to interact with translin [, ]. |
