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Protein Domain : E2 binding

Primary Identifier  IPR014929 Type  Domain
Short Name  E2-binding
description  E1 and E2 enzymes play a central role in ubiquitin and ubiquitin-like protein transfer cascades. This is an E2 binding domain that is found on NEDD8 activating E1 enzyme. The protein resembles ubiquitin, and recruits the catalytic core of the E2 enzyme Ubc12 in a similar manner to that in which ubiquitin interacts with ubiquitin binding domains [].

0 Child Features

0 Parent Features

6 Protein Domain Regions