Primary Identifier | IPR030264 | Type | Family |
Short Name | CLIC-5 |
description | CLIC5 belongs to a family of six vertebrate chloride intracellular channel (CLIC) proteins, all sharing a conserved C-terminal CLIC module []. CLIC5 associates with the cortical actin cytoskeleton [, ]. It is strongly and reversibly inhibited by cytosolic F-actin []. The isoform CLIC5A is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture []. |