Primary Identifier | IPR031176 | Type | Family |
Short Name | ELL/occludin |
description | This entry represents the ELL/occludin family. Occludin is found in the tight junction and may play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier []. ELL is a family of RNA polymerase II elongation factors. It is bound stably to elongation-associated factors 1 and 2, EAFs, and together these act as a strong regulator of transcription activity by direct interaction with Pol II. ELL binds to pol II on its own but the affinity is greatly increased by the cooperation of EAF []. |