| Primary Identifier | IPR026933 | Type | Family |
| Short Name | MRF |
| description | This entry represents metazoan myelin gene regulatory factor (MRF). MRF is a transcription regulator required in vertebrates for expression of central nervous system (CNS) myelin genes such as Mbp and Mog, thereby playing a central role in oligodendrocyte maturation and CNS myelination []. It is also required for the maintenance of expression of myelin genes and the mature oligodendrocytes identity in the adult CNS []. A Caenorhabditis elegans orthologue, pqn-47, may function as a regulator of molting [], while a Dictyostelium orthologue has been described to regulate prestalk differentiation []. |
