Primary Identifier | IPR012361 | Type | Family |
Short Name | GalT_short |
description | This group is related to , galactose-1-phosphate uridylyltransferases (GalT; ). is a member of the HIT domain superfamily based on structural fold []and has a signature HXHXQ. Members of this group are shorter than members by ~100 residues, but have considerable sequence similarity, including the signature. Galactose-1-phosphate uridylyltransferase is involved in the metabolism of galactose via the Leloir pathway []. GalT catalyses the transfer of a uridine 5 -phosphoryl group from UDP-galactose 1-phosphate. It consists of two identical subunits; the active site is formed by amino acid residues from both subunits of the dimer [, ]. |