Primary Identifier | IPR024225 | Type | Conserved_site |
Short Name | cAMP-PdiesteraseII_CS |
description | Cyclic-AMP phosphodiesterase () (PDE) catalyses the hydrolysis of cAMP to the corresponding nucleoside 5' monophosphate. On the basis of sequence similarity, most PDEs can be grouped together [], but some enzymes lie apart from the main family and represent a second distinct class []that includes PDEs from Dictyostelium and yeast. In the central part of these enzymes there is a highly conserved site which contains three histidines. This entry represents that conserved site. |