Primary Identifier | IPR038867 | Type | Family |
Short Name | WAC |
description | WAC interacts with RNF20/40 through its C-terminal coiled-coil region and promotes RNF20/40 s E3 ligase activity for H2B ubiquitination []. Drosophila WAC, also known as Wacky, promotes the interaction between TTT and Pontin/Reptin, thereby promoting mTORC1 activity by facilitating mTORC1 dimerization and mTORC1-Rag interaction []. |