| Primary Identifier | IPR044502 | Type | Family |
| Short Name | AtHST-like |
| description | This entry represents a group of plant members of the UbiA family of prenyltransferases, including AtHST from Arabidopsis. AtHST catalyses the prenylation and decarboxylation of homogentisate to form 2-methyl-6-solanesyl-1,4-benzoquinol, the first intermediate in plastoquinone-9 biosynthesis []. This entry also includes naringenin 8-dimethylallyltransferase [], glycinol 4-dimethylallyltransferase []and 2-acylphloroglucinol 4-prenyltransferase [], which share significant homology with homogentisate prenyltransferases.Prenyltransferases (PTs) catalyse the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways. Plant aromatic PTs can be divided into two distinct sub-groups: one is 4-hydroxybenzoate PTs, which are involved in ubiquinone (benzoquinone) and naphthoquinone derivatives localised in mitochondria or the endoplasmic reticulum, and the second sub-group comprises members of the homogentisate PT (HGPT) family, which are involved in vitamin E and plastoquinone biosynthesis []. |
